Low-Grade Appendiceal Mucinous Neoplasm: Case Reports and a Review of Literature

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<p>Background: Low-grade appendiceal mucinous neoplasm (LAMN) is rare. Since it can progress to peritoneal pseudomyxoma or mucinous carcinoma, appropriate diagnosis and therapy are needed. Three LAMN cases in various stages that presented within only one year to our hospital are presented.</p><p>Case presentation: Case 1 was a 75-year-old woman with right lower quadrant abdominal pain. She was diagnosed with a mucinous mucocele of the appendix and underwent ileocecal resection. Case 2 was a 67-year-old man diagnosed with chronic appendicitis who underwent appendectomy. Case 3 was a 75-year-old man who was found to have a tumor of the appendix on a periodic examination after gastric cancer surgery and underwent ileocecal resection. These three cases were diagnosed with LAMN, and their surgical margins were negative on pathology. None of them have had recurrence.</p><p>Conclusion: There are no therapeutic guidelines for LAMN. However, since it has malignant potential, correct diagnosis and optimal surgical therapy are needed. Since LAMN can be seen even in small hospitals, these cases are reported along with a review of the relevant literature.</p>

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