Analysis of Bacterial Laboratory Evolution toward Prediction, Control, and Macroscopic State Theory of Evolution
-
- FURUSAWA Chikara
- Center for Biosystems Dynamics Research, RIKEN Universal Biology Institute, The University of Tokyo
-
- HORINOUCHI Takaaki
- Center for Biosystems Dynamics Research, RIKEN
Bibliographic Information
- Other Title
-
- 微生物進化実験の定量解析:予測・制御・細胞状態論へ向けて
- ビセイブツ シンカ ジッケン ノ テイリョウ カイセキ : ヨソク ・ セイギョ ・ サイボウ ジョウタイロン エ ムケテ
Search this article
Abstract
<p>During adaptive evolution, phenotype and genotype dynamically change; however, the relationship between these changes and associated constraints is yet to be fully elucidated. In this review, we focus on the analysis of phenotypic and genotypic changes occurred in Escherichia coli cells during laboratory evolution experiments. We demonstrated that the change of fitness can be quantitatively predicted by the expression changes of a small number of genes, suggesting that phenotypic changes in adaptive evolution are constrained on relatively low-dimensional dynamics. The automated system for laboratory evolution is also presented, which enables us to achieve large-scale data in bacterial adaptive evolution.</p>
Journal
-
- Seibutsu Butsuri
-
Seibutsu Butsuri 59 (5), 262-265, 2019
The Biophysical Society of Japan General Incorporated Association
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282752334132352
-
- NII Article ID
- 130007718911
-
- NII Book ID
- AN00129693
-
- ISSN
- 13474219
- 05824052
-
- NDL BIB ID
- 030043660
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
-
- Abstract License Flag
- Disallowed