Antimicrobial-resistant bacteria, phage therapy and Patterson’s case

  • Iwano H.
    Laboratory of Biochemistry, School of Veterinary Medicine, Rakuno Gakuen University
  • Fujiki J.
    Laboratory of Biochemistry, School of Veterinary Medicine, Rakuno Gakuen University
  • Nakamura N.
    Laboratory of Biochemistry, School of Veterinary Medicine, Rakuno Gakuen University
  • Gondaira S.
    Laboratory of Veterinary Hygiene, School of Veterinary Medicine, Rakuno Gakuen University
  • Higuchi H.
    Laboratory of Veterinary Hygiene, School of Veterinary Medicine, Rakuno Gakuen University

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Other Title
  • ファージセラピーの現状と動物医療への応用
  • ファージセラピー ノ ゲンジョウ ト ドウブツ イリョウ エ ノ オウヨウ

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Abstract

<p> Although various approaches have been developed and tried to control the spread of antimicrobial resistance(AMR), a definitive strategy is yet to be established. Phage therapy that has been used for many years in the Eastern European countries is attracting a renewed attention as a promising approach against AMR. In the United States, the recent cure of Tom Patterson, who was in a critical condition from an infection with multidrug-resistant Acinetobacter baumannii, has accelerated the clinical application of phage therapy. In the present paper, we will provide an overview of phage therapy, review its potential clinical problems learned from Patterson’s case and discuss its possibilities in veterinary medicine.</p>

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