Perineuritis Successfully Treated with Early Aggressive Immunotherapy
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- Nakamura Takumi
- Department of Neurology, Hirosaki University Graduate School of Medicine, Japan
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- Kawarabayashi Takeshi
- Department of Neurology, Hirosaki University Graduate School of Medicine, Japan
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- Seino Yusuke
- Department of Neurology, Hirosaki University Graduate School of Medicine, Japan
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- Hirohata Mie
- Department of Neurology, Hirosaki University Graduate School of Medicine, Japan
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- Wakabayashi Koichi
- Department of Neuropathology, Hirosaki University Graduate School of Medicine, Japan
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- Shoji Mikio
- Department of Neurology, Hirosaki University Graduate School of Medicine, Japan
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Abstract
<p>Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms. </p>
Journal
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- Internal Medicine
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Internal Medicine 58 (19), 2875-2878, 2019-10-01
The Japanese Society of Internal Medicine
