Usefulness of Venous Pressure Measurement in Endovascular Treatment of Budd-Chiari Syndrome: A Retrospective Cohort Study
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- Kageyama Ken
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Yamamoto Akira
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Jogo Atsushi
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Nota Takehito
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Murai Kazuki
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Ogawa Satoyuki
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Nakano Mariko M.
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Sohgawa Etsuji
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Hamamoto Shinichi
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
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- Hamuro Masao
- Department of Radiology, Izumiotsu Municipal Hospital, Japan
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- Kaminou Toshio
- Department of Radiology, National Hospital Organization Osaka Minami Medical Center, Japan
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- Nishida Norifumi
- Department of Radiology, Osaka Saiseikai Nakatsu Hospital, Japan
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- Takahashi Kanae
- Department of Medical Statistics, Osaka City University Graduate School of Medicine, Japan
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- Yamamoto Kouji
- Department of Medical Statistics, Osaka City University Graduate School of Medicine, Japan
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- Miki Yukio
- Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine, Japan
抄録
<p>Objective Therapeutic predictors derived from the venous pressure before therapy have not been identified for Budd-Chiari syndrome (BCS). The aim of this study was to determine whether or not measuring the distal pressure or pressure gradient was useful for predicting treatment efficacy in BCS. </p><p>Methods We retrospectively analyzed seven consecutive patients diagnosed with symptomatic BCS at our hospital between 2008 and 2017. Distal and proximal venous pressures at occlusion sites of BCS were measured before treatment in all cases. The pressure gradient was defined as the difference between distal and proximal venous pressures. A receiver operating characteristics (ROC) analysis was performed for venous pressures. </p><p>Results Percutaneous old balloon angioplasty (POBA) was performed in seven cases, with technical success achieved in all cases (100%). No complications were encountered. The median primary patency was 574 (interquartile range, 439.5-1,056.5) days. The 1-year primary patency rate was 71.73%. Six cases (85.7%) showed resolution of symptoms, representing clinical success. The ROC analysis revealed a high distal pressure (area under the ROC curve = 0.83, cut-off=12 mmHg) as a predictor of treatment efficacy of POBA for symptomatic BCS. In addition, the pressure gradient was considered significant from a clinical perspective, because the 6 successful cases with resolution of symptoms showed a large pressure gradient (range, 8-21 mmHg) before treatment, whereas the failed case showed a relatively small pressure gradient (7 mmHg). </p><p>Conclusion High distal pressure and a large pressure gradient might predict the treatment efficacy of balloon angioplasty for symptomatic BCS. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 58 (20), 2923-2929, 2019-10-15
一般社団法人 日本内科学会