Examination of precipitation and sedimentation in quantity-restricted cold aqueous suspensions of granular Japanese herbal extracts commonly used during palliative and supportive care

DOI Web Site Open Access
  • MATSUOKA Yuriko
    Department of Anesthesiology, National Hospital Organization Osaka Toneyama Medical Center Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine
  • NAKANISHI Miho
    Department of Anesthesiology, Shiga University of Medical Science

Bibliographic Information

Other Title
  • がんの支持療法や緩和医療における漢方薬治療―低温少量水での漢方エキス顆粒の懸濁時沈殿率について―
  • ガン ノ シジ リョウホウ ヤ カンワ イリョウ ニ オケル カンポウヤク チリョウ : テイオン ショウリョウスイ デ ノ カンポウ エキス カリュウ ノ ケンダクジ チンデンリツ ニ ツイテ

Search this article

Abstract

<p>Purpose: To ensure controlled dosage of Japanese herbal medicines given in small quantities of water, sedimentation must be minimized. When anorexia or nausea are present, medicinal-extract suspensions in cold water are consumed more easily; finding no reports on this, we examined how sedimentation of different medications varied in icy-cold to lukewarm water. Method: Into separate 20 ml syringes, each containing 15 ml of distilled water at either 0℃, 20℃ or 40℃, we dropped half a sachet of each of 24 types of herbal extract granules. At just after and 5 min after suspension, the samples were agitated for 1 min; at 10 min after suspension, sedimentation was measured. Results: At 0℃ and 20℃, nine formulations showed no more sedimentation than at 40℃; of these, one had no macroscopic sedimentation at any sampling temperature. Conclusion: Some Japanese herbal formulations may be effectively administered in cool and cold water.</p>

Journal

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top