Fluorescent Sensors Based on a Novel Functional Design: Combination of an Environment-sensitive Fluorophore with Polymeric and Self-assembled Architectures
-
- 内山 聖一
- Graduate School of Pharmaceutical Sciences, The University of Tokyo
この論文をさがす
抄録
<p>The fluorescence properties, e.g., fluorescence intensity, of fluorescent sensors can change due to covalent derivatization or noncovalent complexation with a target chemical species (i.e., molecules and ions) or by variations in circumstantial physical parameters (e.g., temperature and viscosity). The internal charge transfer (ICT) character and photoinduced electron transfer (PET) efficiency can be used to tune the fluorescence switching mechanism, facilitating the development of new fluorescent sensors. In addition, the utilization of an environment-sensitive (i.e., polarity- and hydrogen bonding-sensitive) fluorophore in stimulus-responsive macromolecules to design novel fluorescent sensors has been proposed. Based on this concept, highly sensitive fluorescent polymeric thermometers and (extremely sensitive) digital fluorescent pH sensors have been developed. These thermometers are being used to measure the temperature of live cells in biological and medical studies. This concept has also allowed nanoscale proton mapping near membranes, which exemplifies the downsizing of targets for fluorescent sensing from a micrometer-scale to a nanometer-scale.</p>
収録刊行物
-
- 有機合成化学協会誌
-
有機合成化学協会誌 77 (11), 1116-1127, 2019-11-01
公益社団法人 有機合成化学協会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282752362103808
-
- NII論文ID
- 130007742537
-
- NII書誌ID
- AN0024521X
-
- ISSN
- 18836526
- 00379980
-
- NDL書誌ID
- 030109907
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
-
- 抄録ライセンスフラグ
- 使用不可