Impact of Trigger on Outcome of Takotsubo Syndrome ― Multi-Center Registry From Tokyo Cardiovascular Care Unit Network ―
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- Imori Yoichi
- Tokyo Cardiovascular Care Unit Network Scientific Committee Department of Cardiovascular Medicine, Nippon Medical School Hospital
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- Yoshikawa Tsutomu
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Murakami Tsutomu
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Isogai Toshiaki
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Yamaguchi Tetsuo
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Maekawa Yuichiro
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Sakata Konomi
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Mochizuki Hiroki
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Arao Kenshiro
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Otsuka Toshiaki
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Nagao Ken
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Yamamoto Takeshi
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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- Takayama Morimasa
- Tokyo Cardiovascular Care Unit Network Scientific Committee
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<p>Background:The relationship between outcome and trigger in takotsubo syndrome (TTS) has been recently discussed, but the data are still limited.</p><p>Methods and Results:We enrolled 745 consecutive patients with TTS from the Tokyo Cardiovascular Care Unit Network registry. The patients were divided into 4 groups based on trigger: (1) medical illness, 202 (27%); (2) physical activity, trauma and injury, 54 (7%); (3) emotional trigger, 199 (27%); and (4) unidentifiable trigger, 290 (39%). Compared with other groups, the medical illness group had the lowest percentage of female patients (68%, 85%, 89%, and 79%, respectively; P<0.001) and the highest mean patient age (75±11 years, 72±11, 73±12, and 75±11 years, respectively; P=0.02). In-hospital all-cause mortality was higher (11%) in this group (0%, 2%, and 2%, respectively; P<0.001). On multivariate logistic regression analysis, the medical illness group independently predicted all-cause death (OR, 4.73; 95% CI: 1.33–16.87); although there was no significant difference in cardiac deaths between the 4 groups.</p><p>Conclusions:TTS has a wide spectrum of outcome depending on the trigger. The medical illness trigger was a powerful predictor of outcome but the main cause of death is not cardiac complication.</p>
収録刊行物
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- Circulation Reports
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Circulation Reports 1 (11), 493-501, 2019-11-08
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390845702319580928
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- NII論文ID
- 130007742735
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- ISSN
- 24340790
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
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- 使用不可