Phase Separation and Collection of Annular Flow by Phase Transformation

• YOSHIOKA Aya

  Applied Chemistry, Graduate School of Science and Engineering, Doshisha University

• TSUKAGOSHI Kazuhiko

  Applied Chemistry, Graduate School of Science and Engineering, Doshisha University

• TSUCHIYA Katsumi

  Applied Chemistry, Graduate School of Science and Engineering, Doshisha University

• HIROTA Ken

  Applied Chemistry, Graduate School of Science and Engineering, Doshisha University

• YAMASHITA Kenichi

  Advanced Manufacturing Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)

• MURATA Masaharu

  Department of Advanced Medical Initiatives, Faculty of Medical Sciences, Kyushu University

Bibliographic Information

Other Title

• Advancements in Instrumentation : Phase Separation and Collection of Annular Flow by Phase Transformation

Abstract

A polyethylene glycol/citrate mixed solution was fed into a single channel of a Y-type micro-channel on a microchip as an aqueous two-phase system. A phase separation multi-phase flow with a liquid–liquid interface was generated due to a phase transformation. An annular flow, one of the flow types in the phase separation multi-phase flow, was observed through bright-field microscopy. The flow consisted of citrate-rich inner and polyethylene glycol-rich outer phases. We attempted to separate and collect the two phases in the single channel into two separate Y-type channels. When the pressure losses for the separated channels were not very different, we observed symmetric flow in the Y-type channel. When the pressure losses were quite different, the polyethylene glycol-rich phase with higher viscosity was selectively distributed to the separated channel with lower pressure loss. Thus, the polyethylene glycol-rich phase was successfully and intentionally collected from the chosen Y-type channel via the creation of annular flow in the single channel.

Journal

• Analytical Sciences

  Analytical Sciences 35 (11), 1279-1282, 2019-11-10

  The Japan Society for Analytical Chemistry

Keywords

• Phase separation multi-phase flow
• polyethylene glycol
• trisodium citrate
• Y-type micro-channel
• tube radial distribution flow

Details

• CRID: 1390282752367958400
• NII Article ID: 130007743080
• NII Book ID: AA10500785
• DOI: 10.2116/analsci.19a001
• ISSN: 13482246
• ISSN: 09106340
• NDL BIB ID: 030079166
• PubMed: 31308295
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I030079166
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.19A001.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.19A001/fulltext.html
• Web Site: https://www.jstage.jst.go.jp/article/analsci/35/11/35_19A001/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed