Simultaneous Occurrence of Sarcoidosis and Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis in a Patient with Lung Cancer
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- Tsuchiya Kazuo
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan Department of Tumor Pathology, Hamamatsu University School of Medicine, Japan
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- Karayama Masato
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Japan
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- Sato Taichi
- First Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Yasui Hideki
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Hozumi Hironao
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Suzuki Yuzo
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Furuhashi Kazuki
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Enomoto Noriyuki
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Fujisawa Tomoyuki
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Nakamura Yutaro
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Inui Naoki
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Sugimura Haruhiko
- Department of Tumor Pathology, Hamamatsu University School of Medicine, Japan
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- Yasuda Hideo
- First Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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- Suda Takafumi
- Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Japan
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抄録
<p>A 71-year-old woman with abnormal pulmonary shadows and multiple enlarged thoracic lymph nodes was diagnosed with stage IIB lung adenocarcinoma, pulmonary sarcoidosis, and sarcoidosis-associated lymphadenopathy after biopsies from multiple organ sites. She also had rapidly progressive renal dysfunction, microhematuria, and high myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) concentrations. A renal biopsy revealed granulomatous tubulointerstitial nephritis and necrotizing glomerulonephritis with crescent formation. She was diagnosed with nephritis caused by both sarcoidosis and ANCA-associated vasculitis. Oral prednisolone was administered to treat her nephritis, resulting in improvement in both her renal dysfunction and her sarcoidosis-associated lymphadenopathy. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 58 (22), 3299-3304, 2019-11-15
一般社団法人 日本内科学会