書誌事項
- タイトル別名
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- Oral ulcers suspected to be caused by improper administration of bisphosphonate
- ビスフォスフォネート セイザイ ノ フテキセツ ナ フクヨウ ホウホウ ニ ヨル ハッショウ ガ ウタガワレタ コウコウ ネンマク カイヨウ
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<p>The side effects of peroral bisphosphonate may cause mucous membrane disorders and oral exulceration if individuals dissolve the drug inside the oral cavity on oral administration. We experienced two cases in which we strongly suspected mucous ulcurs due to this drug. Finally, the oral exulceration disappeared after providing instructions on correct administration.</p><p> An 83-year-old woman was referred because of exulceration of the right mandible. She suffered from osteoporosis, thoracic vertebra compression fracture, and dementia, while taking alendronate weekly. The exulceration appeared from the right lower lip to the right mandibular molar gingiva when we absorbed pooled saliva in the right oral cavity when the patient was lying down. We instructed the patient to confirm that the tablet was completely swallowed. The ulcers in the oral cavity completely disappeared 17 days after presentation.</p><p> A 74-year-old woman with osteoporosis presented because of bleeding and pain in the gingiva of the right mandible. She was taking monthly minodronate while wearing incompatible dentures. Exulceration occurred with peripheral redness ranging from the right buccal mucosa to the right molar gingiva of the mandible and the tongue/floor of her mouth, along with a ventrolateral tongue. We taught her how to swallow minodoronate correctly without dentures, and the ulcers healed 4 weeks later.</p>
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 65 (9), 599-604, 2019-09-20
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390845702324796800
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- NII論文ID
- 130007748571
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 030006116
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 使用不可