Familial Mediterranean Fever Is Important in the Differential Diagnosis of Recurrent Aseptic Meningitis in Japan

DOI IR IR HANDLE HANDLE View 2 Remaining Hide 1 Citations 9 References Open Access
  • Hosoi Takahiro
    Department of General Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan
  • Ishii Kazuhiro
    Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan
  • Tozaka Naoki
    Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan
  • Kishida Dai
    Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan
  • Sekijima Yoshiki
    Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan
  • Tamaoka Akira
    Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan

Search this article

Abstract

<p>Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by a recurrent fever and multiple serositis. In the present report, we discuss the case of a 42-year-old man diagnosed with FMF accompanied by recurrent aseptic meningitis (RAM). The patient experienced RAM at intervals of several years without any serositis or synovitis. We detected Mediterranean fever (MEFV) gene mutations (E148Q homozygotes) and diagnosed FMF in perfect accordance with clinical diagnostic criteria. FMF, in which RAM is a major symptom, has also been described in previous reports. Therefore, FMF should be considered in the differential diagnosis of causative diseases for RAM. </p>

Journal

  • Internal Medicine

    Internal Medicine 59 (1), 125-128, 2020-01-01

    The Japanese Society of Internal Medicine

Citations (1)*help

See more

References(9)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top