頸動脈微小栓子シグナル(一過性高輝度信号)検出を契機に経食道心エコー法を行い大動脈弓部に線虫感染が疑われた若年性多発性皮質下変性の1例

  • 榛沢 和彦
    新潟大学医歯学総合研究科先進血管病・塞栓症治療・予防講座
  • 伊倉 真衣子
    新潟大学医歯学総合研究科先進血管病・塞栓症治療・予防講座
  • 森下 篤
    沼田脳神経外科循環器科病院心臓血管外科
  • 西松 輝高
    沼田脳神経外科循環器科病院脳神経外科
  • 赤尾 法彦
    沼田脳神経外科循環器科病院脳神経外科

書誌事項

タイトル別名
  • A case of juvenile multiple subcortical lesions with suspicious of <i>Angiostrongylus</i> infection of the aortic arch by transesophageal echocardiography with high intensity transient signals detected in the carotid artery

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A 21-year-old Indonesian woman came to hospital with severe headache and vomiting. Brain MRI showed multiple subcortical lesions. High-intensity transient signals (HITS) was detected in the carotid artery and transesophageal echocardiography (TEE) was performed to search for embolic sources. Mobile string-like structures were found in the aortic arch. We started anticoagulation therapy. One month later, TEE reexamination revealed that the aortic arch cord had shrunk, but numerous cords were found in the pulmonary artery. She was suspected with Angiostrongylus cantonensis infection and treated with antiparasitic agent and steroids. One month later, the TEE was performed again, and the cord-like structure in the aortic arch almost disappeared, and the abnormal structure in the pulmonary artery also disappeared. It is known that A. cantonensis can cause eosinophilic meningoencephalitis, but its prognosis is good, and it is thought that it may be mild. In this case, although the definitive diagnosis has not been made, the possibility was considered to be high because antiparasitic agent was effective. HITS detection for investigating the cause of multiple subcortical lesions was considered to be useful in determining the embolic mechanism.

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