Impact of introducing the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria on pregnancy outcomes in Japan
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- Shindo Ryosuke
- Perinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan
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- Aoki Shigeru
- Perinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan
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- Kasai Junko
- Perinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan
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- Saigusa Yusuke
- Department of Biostatistics, Yokohama City University Graduate School of Medicine, Yokohama, Japan
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- Nakanishi Sayuri
- Perinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan
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- Miyagi Etsuko
- Department of Obstetrics and Gynecology, Yokohama City University School of Medicine, Yokohama, Japan
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抄録
<p>To estimate pregnancy complications in women newly diagnosed with gestational diabetes mellitus (GDM) according to the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and verify the validity of introducing the IADPSG criteria in Japan. This retrospective study included data from women with singleton delivery at 22 weeks or later at a tertiary hospital during 2000–2009. We compared pregnancy outcomes between women who would now be diagnosed with GDM according to the IADPSG criteria but not by the old JSOG criteria (IGT group, n = 503) and women with normal glucose tolerance according to both the criteria (NGT group, n = 2,789). Multivariate analysis was performed and adjusted for background factors. Maternal age at delivery and pre-pregnancy BMI were significantly higher in the IGT group than in the NGT group, while gestational weeks at delivery did not differ between the groups. No difference was observed in the rates of GDM-related composite complications (defined as cases with at least one of the following: macrosomia, shoulder dystocia, neonatal hypoglycemia, neonatal hyperbilirubinemia, or neonatal respiratory distress syndrome) at 11.9% and 8.8% (adjusted odds ratio (OR) 1.30, 95% confidence interval (CI) 0.90–1.87, p = 0.16). Pregnancy outcomes did not differ significantly between the IGT and NGT groups, except for frequencies of total neonatal admissions at 10.5% and 7.1%, respectively (adjusted OR 1.55, 95% CI 1.12–2.13, p < 0.01).</p>
収録刊行物
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- Endocrine Journal
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Endocrine Journal 67 (1), 15-20, 2020
一般社団法人 日本内分泌学会