Pathological and Radiological Correlation in Prolonged Myeloperoxidase Anti-neutrophil Cytoplasmic Antibody-related Diffuse Alveolar Hemosiderosis
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- Saraya Takeshi
- Department of Respiratory Medicine, Kyorin University School of Medicine, Japan
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- Fujiwara Masachika
- Department of Pathology, Kyorin University School of Medicine, Japan
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- Yokoyama Takuma
- Department of Respiratory Medicine, Kyorin University School of Medicine, Japan
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- Takata Saori
- Department of Respiratory Medicine, Kyorin University School of Medicine, Japan
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- Oka Teruaki
- Department of Pathology, Kanto Central Hospital of the Mutual Aid Association of Public School Teachers, Japan
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- Ishii Haruyuki
- Department of Respiratory Medicine, Kyorin University School of Medicine, Japan
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- Takizawa Hajime
- Department of Respiratory Medicine, Kyorin University School of Medicine, Japan
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抄録
<p>A 60-year-old woman with a 20-year history of myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis visited our hospital due to productive cough and a low-grade fever for several weeks. Thoracic computed tomography demonstrated scattered tiny nodules, patchy consolidation, ground glass opacities, and thickening interlobular septa. On video-assisted thoracic surgery, those abnormalities were found to correspond to the accumulation of hemosiderin-laden alveolar macrophages (AMs) in the alveolar spaces and alveolar septa due to MPO-ANCA vasculitis. The radiological findings persisted for a further two years, indicating the possibility of persistent vasculitis in the lung or evidence of incomplete clearance of hemosiderin-laden AMs. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 59 (3), 415-419, 2020-02-01
一般社団法人 日本内科学会
