Analysis Method of the Ion Current–Time Waveform Obtained from Low Aspect Ratio Solid-state Nanopores

• TANIGUCHI Masateru

  The Institute of Scientific and Industrial Research, Osaka University

抄録

Low aspect ratio nanopores are expected to be applied to the detection of viruses and bacteria because of their high spatial resolution. Multiphysics simulations have revealed that the ion current–time waveform obtained from low aspect ratio nanopores contains information on not only the volume of viruses and bacteria, but also the structure, surface charge, and flow dynamics. Analysis using machine learning extracts information about these analytes from the ion current–time waveform. The combination of low aspect ratio nanopores, multiphysics simulation, and machine learning has made it possible to distinguish different types of viruses and bacteria with high accuracy.

収録刊行物

• Analytical Sciences

  Analytical Sciences 36 (2), 161-175, 2020-02-10

  社団法人 日本分析化学会

キーワード

• Low aspect nanopores
• solid-state nanopores
• virus
• bacteria
• multiphysics
• machine learning

詳細情報

• CRID: 1390846609803713408
• NII論文ID: 130007796148
• NII書誌ID: AA10500785
• DOI: 10.2116/analsci.19r009
• ISSN: 13482246
• ISSN: 09106340
• NDL書誌ID: 030249649
• PubMed: 31813895
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I030249649
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.19R009.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.19R009/fulltext.html
• Web Site: https://www.jstage.jst.go.jp/article/analsci/36/2/36_19R009/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可