Brain Abscess as a Rare Complication of Primary Extranodal Nasal-type Natural Killer/T-cell Lymphoma

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  • Ohta Nobuo
    Division of Otolaryngology, Tohoku Medical and Pharmaceutical University, Sendai 981-0905, Japan
  • Waki Takayoshi
    Department of Otolaryngology, Head and Neck Surgery, Yamagata University, Yamagata 990-1122
  • Ito Tsukasa
    Department of Otolaryngology, Head and Neck Surgery, Yamagata University, Yamagata 990-1122
  • Suzuki Yusuke
    Department of Otolaryngology, Head and Neck Surgery, Yamagata University, Yamagata 990-1122
  • Kakehata Seiji
    Department of Otolaryngology, Head and Neck Surgery, Yamagata University, Yamagata 990-1122
  • Aoyagi Masaru
    Department of Otolaryngology, Head and Neck Surgery, Yamagata University, Yamagata 990-1122

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<p>We present the case of a 58-year-old Japanese woman with a natural killer T (NK/T)-cell lymphoma complicated by brain abscess. NK/T-cell lymphomas represent a rare type of lymphoma derived from either activated NK cells or, rarely, cytotoxic T cells. They are aggressive Epstein-Barr virus (EBV)-associated lymphomas that involve mainly the nasal cavity. Brain abscess associated with primary extranodal nasal-type NK/T-cell lymphoma is extremely uncommon: to our knowledge, this is the first reported case of this lymphoma with brain abscess as the initial clinical manifestation. Endoscopic surgery was performed for definitive diagnosis under intraoperative navigation system. Chemotherapy followed by radiotherapy was performed and was effective: 72 months later the tumor has not recurred. Recommendations of endoscopic management for diagnosis and treatment of this rare neoplasm are discussed.</p>

収録刊行物

  • Yonago Acta Medica

    Yonago Acta Medica 63 (1), 88-91, 2020

    ヨナゴ・アクタ・メディカ刊行会

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