Health Related Quality of Life in Japanese Patients with Localized Prostate Cancer: Comparative Retrospective Study of Robot-Assisted Laparoscopic Radical Prostatectomy Versus Radiation Therapy

• Miyoshi Yoko

  Department of Adult and Elderly Nursing, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan

• Morizane Shuichi

  Department of Urology, Tottori University Hospital, Yonago 683-8504, Japan

• Honda Masashi

  Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan

• Hikita Katsuya

  Department of Urology, Tottori University Hospital, Yonago 683-8504, Japan

• Iwamoto Hideto

  Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan

• Yumioka Tetsuya

  Department of Urology, Matsue City Hospital, Matsue 690-8509, Japan

• Kimura Yusuke

  Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan

• Yoshioka Shin-ichi

  Department of Nursing Care Environment and Mental Health, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan

• Takenaka Atsushi

  Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan

Abstract

Background Radical prostatectomy and radiotherapy are standard treatments for localized prostate cancer. When making decisions about treatment, it is important to not only consider medical information such as the patient’s age, performance status, and complications, but also the impact on quality of life (QOL) after treatment. Our purpose was to compare health related quality of life (HRQOL) after robot-assisted laparoscopic radical prostatectomy (RARP) versus radiation therapy in Japanese patients with localized prostate cancer retrospectively. Methods Patients with localized prostate cancer receiving RARP or radiotherapy at Tottori University Hospital between October 2010 and December 2014 were enrolled in a retrospective observational study with follow-up for 24 months to December 2016. The Medical Outcome Study 8-Item Short-Form Health Survey was performed before treatment and 1, 3, 6, 12, and 24 months post-treatment. Results Complete responses to the questionnaire were obtained from 154/227 patients receiving RARP, 41/67 patients receiving intensity-modulated radiation therapy, 35/82 patients receiving low dose rate brachytherapy, and 18/28 patients given low dose rate brachytherapy plus external beam radiation therapy. The median physical component summary score of the Medical Outcome Study 8-Item Short-Form Health Survey was significantly lower at 1 month after prostatectomy than radiotherapy, but was similar for both treatments at 3 months, and was significantly higher at 6, 12 and 24 months after prostatectomy. The median mental component summary score was also significantly lower in the prostatectomy group at 1 month, but not from 3 months onwards. Conclusion Our study suggested that HRQOL was inferior at 1 month after RARP, however, recovered at 3 months after RARP and was better than after radiotherapy at 6, 12, and 24 months.

Journal

• Yonago Acta Medica

  Yonago Acta Medica 63 (1), 55-62, 2020

  Tottori University Medical Press

Keywords

• health related quality of life
• Medical Outcome Study 8-Item Short Form Health Survey
• prostate cancer
• prostatectomy
• radiation therapy

Details

• CRID: 1390283659853353856
• NII Article ID: 130007800477
• NII Book ID: AA00892882
• DOI: 10.33160/yam.2020.02.008
• ISSN: 13468049
• ISSN: 05135710
• Web Site: https://repository.lib.tottori-u.ac.jp/records/4718
• Web Site: https://www.jstage.jst.go.jp/article/yam/63/1/63_2020.02.008/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed