Autoimmune Encephalitis Associated with Anti-gamma-aminobutyric Acid B Receptor Antibodies Mimicking Syncope
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- Kitazaki Yuki
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Ikawa Masamichi
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan Department of Advanced Medicine for Community Healthcare, Faculty of Medical Sciences, University of Fukui, Japan
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- Yamaguchi Tomohisa
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Enomoto Soichi
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan Department of Aging and Dementia, Faculty of Medical Sciences, University of Fukui, Japan
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- Kishitani Toru
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Shirafuji Norimichi
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Hayashi Koji
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Yamamura Osamu
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Nakamoto Yasunari
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan
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- Hamano Tadanori
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan Department of Aging and Dementia, Faculty of Medical Sciences, University of Fukui, Japan
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抄録
<p>Autoimmune encephalitis associated with autoantibodies to the gamma-aminobutyric acid B receptor (GABABR-AE) typically involves limbic symptoms with limbic abnormalities visible in brain magnetic resonance imaging (MRI). We herein report a case of a 48-year-old man with GABABR-AE whose initial presentation was limited to syncope without limbic symptoms or MRI abnormalities. Interestingly, serial MRI also revealed no abnormalities even after the appearance of limbic symptoms. Our findings suggest that GABABR-AE can initially mimic common syncope and that MRI findings may remain normal throughout the clinical course. Even if patients have normal MRI findings, GABABR-AE should be considered if limbic symptoms worsen. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 59 (6), 843-847, 2020-03-15
一般社団法人 日本内科学会