Prevalence of Multidrug Resistant Salmonellae with Increasing Frequency of Salmonella enterica Serovars Kentucky and Virchow among Hospitalized Diarrheal Cases in and around Delhi, India

• Sharma Naresh Chand

  Maharishi Valmiki Infectious Diseases Hospital

• Kumar Dhirendra

  Maharishi Valmiki Infectious Diseases Hospital Center for Human Microbial Ecology, Translational Health Science and Technology Institute

• Sarkar Anirban

  Division of Bacteriology, National Institute of Cholera and Enteric Diseases

• Chowdhury Goutam

  Division of Bacteriology, National Institute of Cholera and Enteric Diseases

• Mukhopadhyay Asish K

  Division of Bacteriology, National Institute of Cholera and Enteric Diseases

• Ramamurthy Thandavarayan

  Center for Human Microbial Ecology, Translational Health Science and Technology Institute

書誌事項

タイトル別名

• Prevalence of Multidrug Resistant Salmonellae with Increasing Frequency of <i>Salmonella enterica</i> Serovars Kentucky and Virchow among Hospitalized Diarrheal Cases in and around Delhi, India

抄録

Non-typhoidal salmonellae (NTS) are a major cause of acute diarrhea with characteristic multidrug resistance (MDR). In a hospital-based study, 81 NTS were isolated and tested for serotypes and antimicrobial resistance (AMR). Salmonella enterica isolates were classified into 7 different typable serovars, however, 19 (23%) isolates remained untypable. The most common serovars were S. Kentucky (48%), and S. Virchow (22%). Most of the NTS isolates displayed resistance to nalidixic acid (NA) (73%), ciprofloxacin (CIP) (48%), ampicillin (AM) and norfloxacin (NOR) (36% each), and gentamicin (CN) (31%). The AMR profiles for CN and NA; and AM, CIP, NA and NOR, were found to be high in S. Virchow (83%) and S. Kentucky (43%), respectively. Analysis of the pulsed-field gel electrophoresis patterns of S. Kentucky revealed 3 clusters. S. Kentucky has clones closely related to become prominent in recent years in Delhi. The AMR appears to be consistent with the change in MDR patterns during 2014-2017. The observed prevalence of S. Kentucky and S. Virchow in large numbers of diarrheal cases is novel. The NTS are mostly resistant to fluoroquinolones, which is the current drug of choice for treating diarrheal cases. MDR is very common among clonally related S. Kentucky.

収録刊行物

• Japanese Journal of Infectious Diseases

  Japanese Journal of Infectious Diseases 73 (2), 119-123, 2020

  国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会

キーワード

• Salmonella
• Serovars
• S.Kentucky
• S.Virchow

詳細情報

• CRID: 1390002184885258240
• NII論文ID: 130007814972
• NII書誌ID: AA1132885X
• DOI: 10.7883/yoken.jjid.2019.063
• ISSN: 18842836
• ISSN: 13446304
• NDL書誌ID: 030368866
• PubMed: 31666490
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I030368866
• Web Site: https://www.jstage.jst.go.jp/article/yoken/73/2/73_JJID.2019.063/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可