The association between detection of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> DNA in feces and histopathological classification
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- TANIGUCHI Yukiko
- Hokkaido Tokachi Livestock Hygiene Service Center, 59-6 Kisen Kawanishicho, Obihiro, Hokkaido 089-1182, Japan
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- SAKAKIBARA Shin-ichi
- Hokkaido Tokachi Livestock Hygiene Service Center, 59-6 Kisen Kawanishicho, Obihiro, Hokkaido 089-1182, Japan Hokkaido Ishikari Livestock Hygiene Service Center, 3 Hitsujigaoka, Toyohira-ku, Sapporo, Hokkaido 062-0045, Japan
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- FUJIHARA Masatoshi
- Hokkiado Livestock Farming Promotion Division, Kita 3 Jo Nishi 6 Chome, Chuo-ku, Sapporo, Hokkaido 060-8588, Japan
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- YAGI Azusa
- Hokkaido Tokachi Livestock Hygiene Service Center, 59-6 Kisen Kawanishicho, Obihiro, Hokkaido 089-1182, Japan Hokkiado Livestock Farming Promotion Division, Kita 3 Jo Nishi 6 Chome, Chuo-ku, Sapporo, Hokkaido 060-8588, Japan
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- FUJIYOSHI Satoshi
- Hokkaido Tokachi Livestock Hygiene Service Center, 59-6 Kisen Kawanishicho, Obihiro, Hokkaido 089-1182, Japan Zen-noh Embryo Transfer Center, 331-11, Nishi 6 Sen, Kamiotofuke, Kamishihoro, Katohgun, Hokkaido 080-1407, Japan
抄録
<p>Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne’s disease (JD), a chronic infectious disease that causes intractable diarrhea in ruminants. To control the occurrence of JD in cattle, a national surveillance is conducted in Japan. Since 2013, real-time quantitative PCR has been used for definite diagnosis. In this study, we compared the amount of fecal MAP DNA with histopathological classification of ileocecal lesions. Multinomial logistic regression models enabled us to predict the probability of finding the histopathological classification from the amount of fecal MAP DNA. These results suggest that shedding level of MAP DNA could act as an indicator of JD progression.</p>
収録刊行物
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- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ
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Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ 82 (5), 541-545, 2020
公益社団法人 日本獣医学会