Two-Year Recurrence After First-Ever Stroke in a General Population of 1.4 Million Japanese Patients ― The Shiga Stroke and Heart Attack Registry Study ―

  • Takashima Naoyuki
    Department of Public Health, Shiga University of Medical Science Department of Public Health, Kindai University Faculty of Medicine
  • Arima Hisatomi
    Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University
  • Kita Yoshikuni
    Department of Public Health, Shiga University of Medical Science Tsuruga Nursing University
  • Fujii Takako
    Department of Neurosurgery, Shiga University of Medical Science Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University
  • Tanaka-Mizuno Sachiko
    Department of Medical Statistics, Shiga University of Medical Science
  • Shitara Satoshi
    Department of Neurosurgery, Shiga University of Medical Science
  • Kitamura Akihiro
    Department of Neurology, Shiga University of Medical Science
  • Miura Katsuyuki
    Department of Public Health, Shiga University of Medical Science Center for Epidemiologic Research in Asia, Shiga University of Medical Science
  • Nozaki Kazuhiko
    Department of Neurosurgery, Shiga University of Medical Science Center for Epidemiologic Research in Asia, Shiga University of Medical Science

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抄録

<p>Background:Despite many effective strategies for the prevention of recurrent stroke, individuals who survive an initial stroke have been shown to be at high risk of recurrent stroke. The aim of this study was to investigate the current status of stroke recurrence after first-ever stroke using a population-based stroke registry in Japan.</p><p>Methods and Results:As part of the Shiga Stroke and Heart Attack Registry, the Shiga Stroke Registry is an ongoing population-based stroke registry study that covers approximately 1.4 million residents of Shiga Prefecture, Japan. A total of 1,883 first-ever stroke survivors at 28 days was registered in 2011 and followed-up until the end of 2013. Recurrence was defined as any type of stroke after 28 days from the onset of an index event. Two-year cumulative recurrence rates were estimated using cumulative incidence function methods. Over a mean 2.1-year follow-up period, 120 patients experienced recurrent stroke and 389 patients died without recurrence. The 2-year cumulative recurrence rate was higher in patients with index ischemic stroke (6.8%) than in those with index hemorrhagic stroke (3.8%).</p><p>Conclusions:Two-year cumulative recurrence rate after first-ever stroke remained high, particularly among patients with ischemic stroke, in the present population-based registry study in a real-world setting in Japan. Further intensive secondary prevention strategies are required for these high-risk individuals.</p>

収録刊行物

  • Circulation Journal

    Circulation Journal 84 (6), 943-948, 2020-05-25

    一般社団法人 日本循環器学会

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