Case study about development of a novel spray-type adhesion barrier system
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- ISHIHARA Hiroyuki
- Terumo Corporation, Corporate R&D Center
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- NIIMI Taishi
- Terumo Corporation, Corporate R&D Center
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- CHINO Naotaka
- Terumo Corporation, Corporate R&D Center
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- KAI Miho
- Terumo Corporation, Corporate R&D Center
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- SOMA Yuki
- Terumo Corporation, Corporate R&D Center
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- WATANABE Eiji
- Ex-Terumo Corporation, Corporate R&D Center
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- KAWANISHI Tetsuro
- Terumo Corporation, Corporate R&D Center
Bibliographic Information
- Other Title
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- 新規癒着防止材の開発事例
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Abstract
<p>We developed a novel spray-type dextrin hydrogel-based adhesion barrier designed to create a site-specific barrier on a target. Our novel hydrogel is composed of Powder A, which mainly contains N-hydroxysuccinimide-modified carboxymethyl dextrin and trehalose as a stabilizing agent, and Powder B, which is composed of sodium carbonate and sodium hydrogen carbonate. The spray device has several unique specifications that can be used under laparoscopic surgery. Furthermore, the shape and the appearance are characteristic so that this device can be appropriately used in a clinical situation. Here, we introduce the development process of a novel spray-type adhesion barrier as the case study of medical device.</p>
Journal
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- PDA Journal of GMP and Validation in Japan
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PDA Journal of GMP and Validation in Japan 22 (1), 6-11, 2020
Parenteral Drug Association Japan Chapter
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Details 詳細情報について
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- CRID
- 1390848250123613952
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- NII Article ID
- 130007865543
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- ISSN
- 18811728
- 13444891
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed