Case study about development of a novel spray-type adhesion barrier system

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  • 新規癒着防止材の開発事例

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<p>We developed a novel spray-type dextrin hydrogel-based adhesion barrier designed to create a site-specific barrier on a target. Our novel hydrogel is composed of Powder A, which mainly contains N-hydroxysuccinimide-modified carboxymethyl dextrin and trehalose as a stabilizing agent, and Powder B, which is composed of sodium carbonate and sodium hydrogen carbonate. The spray device has several unique specifications that can be used under laparoscopic surgery. Furthermore, the shape and the appearance are characteristic so that this device can be appropriately used in a clinical situation. Here, we introduce the development process of a novel spray-type adhesion barrier as the case study of medical device.</p>

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