Occlusal force predicted cognitive decline among 70- and 80-year-old Japanese: A 3-year prospective cohort study

• Hatta Kodai

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Gondo Yasuyuki

  Osaka University Graduate School of Human Sciences, Department of Clinical Thanatology and Geriatric Behavioral Science

• Kamide Kei

  Osaka University Graduate School of Allied Health Sciences

• Masui Yukie

  Tokyo Metropolitan Institute of Gerontology

• Inagaki Hiroki

  Tokyo Metropolitan Institute of Gerontology

• Nakagawa Takeshi

  National Center for Geriatrics and Gerontology

• Matsuda Ken-ichi

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Inomata Chisato

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Takeshita Hajime

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Mihara Yusuke

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Fukutake Motoyoshi

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Kitamura Masahiro

  Osaka University Graduate School of Dentistry, Department of Periodontics

• Murakami Shinya

  Osaka University Graduate School of Dentistry, Department of Periodontics

• Kabayama Mai

  Osaka University Graduate School of Allied Health Sciences

• Ishizaki Tatsuro

  Tokyo Metropolitan Institute of Gerontology

• Arai Yasumichi

  Center for Supercentenarian Medical Research, Keio University School of Medicine

• Sugimoto Ken

  Osaka University Graduate School of Medicine, Department of Geriatric and General Medicine

• Rakugi Hiromi

  Osaka University Graduate School of Medicine, Department of Geriatric and General Medicine

• Maeda Yoshinobu

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

• Ikebe Kazunori

  Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation

抄録

Purpose: Dementia is a growing health problem for countries with aging populations, but few effective dementia treatments are available. However, there is increasing interest in oral health as a modifiable risk factor in interventions to prevent cognitive decline. This study aimed to investigate the impact of oral health on the decline of cognitive function over 3 years among Japanese people aged 70 and 80 years. Methods: Participants (n = 860) were community-dwelling older adults who participated in baseline and follow-up surveys (at baseline: 69-71 years n = 423; 79-81 years, n = 437). Registered dentists examined the number of teeth, number of functional teeth, number of periodontal teeth, and occlusal force. The Japanese version of the Montreal Cognitive Assessment was used to evaluate cognitive function. We also evaluated socioeconomic factors, medical history, drinking and smoking habits, physical performance, genetic factors, and C-reactive protein concentration in blood. A generalized estimating equation (GEE) was used to examine how oral health at baseline influenced cognitive decline over 3 years. Results: The GEE showed that the number of teeth (non-standardized coefficient: B = 0.031, p = 0.022) and occlusal force (B = 0.103, p = 0.004) at baseline were associated with cognitive function at follow-up, even after adjusting for other risk factors. Furthermore, maintaining more teeth (B = 0.009, p = 0.004) and a stronger occlusal force (B = 0.020, p = 0.040) buffered cognitive decline. Conclusions: Number of teeth and occlusal force predict cognitive decline over 3 subsequent years in Japanese older adults aged 70 and 80 years.

収録刊行物

• Journal of Prosthodontic Research

  Journal of Prosthodontic Research 64 (2), 175-181, 2020

  公益社団法人 日本補綴歯科学会

キーワード

• Occlusal force
• Cognitive decline
• Cohort study
• Gerodontology

詳細情報

• CRID: 1390285300173698432
• NII論文ID: 130007871347
• DOI: 10.1016/j.jpor.2019.07.002
• ISSN: 18839207
• ISSN: 18831958
• Web Site: https://api.elsevier.com/content/article/PII:S1883195818302585?httpAccept=text/xml
• Web Site: https://api.elsevier.com/content/article/PII:S1883195818302585?httpAccept=text/plain
• Web Site: https://www.jstage.jst.go.jp/article/jpr/64/2/64_175/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2021042848
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • CiNii Articles
  • KAKEN
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