A Trial Study for Lens Capsule Regeneration Using iPS-derived Cell Aggregates

• Hiramatsu Noriko

  藤田医科大学大学院医学研究科 藤田医科大学研究支援推進本部

• Yamamoto Naoki

  藤田医科大学研究支援推進本部 金沢医科大学医学部眼科学講座

Bibliographic Information

Other Title

• iPS由来細胞凝集体を用いた水晶体囊再生の試み

Abstract

Cell aggregation were differentiated from iPS cells derived from human iris by standstill and rotation culture method, made the section from cell block, and stained hematoxylin and eosin (H.E.) staining, immunostaining of αA-crystalline and p75NTR. Epithelial-like cells were arranged in a monolayer on the surface of the aggregate and strongly express αA-crystalline and p75NTR. Partially observed a part similar to the bow area at the late stage of lens development which is continuously multilayered inward, and a membrane-like structure.

Journal

• The Journal of The Japanese Society for Cataract Research

  The Journal of The Japanese Society for Cataract Research 32 (1), 44-46, 2020

  The Japanese Society for Cataract Research

Keywords

• human iris-derived iPS cells
• lens regeneration
• three-dimensional culture

Details

• CRID: 1390285300173704704
• NII Article ID: 130007871417
• DOI: 10.14938/cataract.12-009
• ISSN: 2188613X
• ISSN: 09154302
• Web Site: https://search.jamas.or.jp/link/ui/2020324283
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed