Simulation and Experiment for Electrode Coverage Evaluation by Electrochemical Impedance Spectroscopy Using Parallel Facing Electrodes
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- TANAKA Shinya
- Department of Electrical Systems, Graduate School of Science and Engineering, Ritsumeikan University
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- KIMURA Kaiken
- Department of Electrical Systems, Graduate School of Science and Engineering, Ritsumeikan University
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- MIYAMOTO Ko-ichiro
- Department of Electronic Engineering, Tohoku University
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- YANASE Yuhki
- Department of Dermatology, Graduate School of Biomedical and Health Science, Hiroshima University
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- UNO Shigeyasu
- Department of Electrical Systems, Graduate School of Science and Engineering, Ritsumeikan University
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<p>A parallel facing electrode (PFE) structure for adherent cell monitoring by electrochemical impedance spectroscopy (EIS) was developed, and its characteristics were investigated by both computer simulation and experiment. The PFE model consists of two facing gold electrode strips separated by 40 μm, and the area of its intersection is 500 × 500 μm. Computer simulation of EIS with adherent cells showed a distinct difference in solution resistance for different cell coverage, which was confirmed by experimental results using latex beads suspension. A well-defined relationship between solution resistance and cell coverage in our PFE is promising for quantitative evaluation of cell density, morphology and fatality.</p>
収録刊行物
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- Analytical Sciences
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Analytical Sciences 36 (7), 853-858, 2020-07-10
社団法人 日本分析化学会
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詳細情報 詳細情報について
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- CRID
- 1390003825197512704
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- NII論文ID
- 130007872092
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- NII書誌ID
- AA10500785
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- ISSN
- 13482246
- 09106340
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- NDL書誌ID
- 030504882
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- PubMed
- 31983717
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可