Antifungal effect of tea extracts on <i>Candida albicans </i>

  • HUANG Jing-jing
    Department of Prosthodontics, School and Hospital of Stomatology, Fujian Medical University
  • YU Hao
    Department of Prosthodontics, School and Hospital of Stomatology, Fujian Medical University Department of Applied Prosthodontics, Graduate School of Biomedical Sciences, Nagasaki University
  • HONG Guang
    Liaison Center for Innovative Dentistry, Graduate School of Dentistry, Tohoku University Faculty of Dental Medicine, Airlangga University
  • CHENG Hui
    Department of Prosthodontics, School and Hospital of Stomatology, Fujian Medical University
  • ZHENG Ming
    Department of Prosthodontics, School and Hospital of Stomatology, Fujian Medical University

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Abstract

<p>Determining whether tea extracts are effective in removing Candida albicans (C. albicans) from dentures is of interest. This study aimed to investigate the antifungal effect of tea extracts on C. albicans. One green tea (Anji white tea, AGW) and 2 oolong teas (Tie Guan Yin, TGY; Da Hong Pao, DHP) of different concentrations were tested. C. albicans suspensions were inoculated on the plates and the numbers of colony-forming units (CFU) in the culture medium were used to screen for the optimum tea extracts. Polymethyl methacrylate (PMMA) specimens that contained C. albicans biofilms were then treated with the tea extracts and the numbers of CFU were counted. The antifungal activities of the tea extracts were not significantly correlated with their catechin concentrations. Although AGW at 10.0 mg/mL and DHP at 2.5 mg/mL significantly inhibited C. albicans in the culture medium, the extracts failed to exert inhibitory effects against C. albicans biofilms on the PMMA surfaces.</p>

Journal

  • Dental Materials Journal

    Dental Materials Journal 39 (4), 664-669, 2020-07-30

    The Japanese Society for Dental Materials and Devices

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