Serodiagnosis of <i>Entamoeba histolytica </i>Infections with an Indirect Haemagglutination Test

• MASUDA Gohta

  Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital

• IMAMURA Akifumi

  Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital

• SEKIYA Noritaka

  Departments of Clinical Laboratory and Infection Prevention and Control, Tokyo Metropolitan Komagome Hospital

• MAEDA Takuya

  Department of Laboratory Medicine, Saitama Medical University

• TACHIBANA Hiroshi

  Department of Parasitology, Tokai University School of Medicine

• KOBAYASHI Seiki

  Department of Infectious Diseases, Keio University School of Medicine

Bibliographic Information

Other Title

• 間接赤血球凝集反応を用いた赤痢アメーバ感染症の血清診断
• カンセツ セッケッキュウ ギョウシュウ ハンノウ オ モチイタ セキリ アメーバ カンセンショウ ノ ケッセイ シンダン

Abstract

Entamoeba histolytica infections comprising enterocolitis (54 cases), liver abscesses (58 cases) and asymptomatic carriers (17 cases) were retrospectively studied based on the medical records of patients diagnosed at the Department of Infectious Diseases of Tokyo Metropolitan Komagome Hospital during 1992-2000, with special reference to serum antibody titers (indirect haemagglutination test) to E. histolytica. As the timing and the frequency of antibody testings varied for each patient, the maximum antibody titers of individual cases were used as the representatives of antibody titers for E. histolytica. Sensitivity of the serodiagnosis to E. histolytica was 85.2% (46 in 54 cases) for amoebic colitis, 98.3% (57 in 58 cases) for amoebic liver abscesses,and 11.8% (2 in 17 cases) for asymptomatic carriers. Following assignation of patients with non-amoebic enterocolitis (28 cases) and non-amoebic space-occupying mass lesions of the liver (16 cases) to negative controls, the specificity of the serodiagnosis with the anti-amoebic antibody was 100% for both groups of the above mentioned patients with amoebic colitis and amoebic liver abscesses.

Journal

• Kansenshogaku Zasshi

  Kansenshogaku Zasshi 94 (1), 102-108, 2020-01-20

  The Japanese Association for Infectious Diseases

Keywords

• <i>Entamoeba histolytica</i>
• amoebic liver abscess
• indirect haemagglutination test

Details

• CRID: 1390848250135198848
• NII Article ID: 130007886412
• NII Book ID: AN00047715
• DOI: 10.11150/kansenshogakuzasshi.94.102
• ISSN: 1884569X
• ISSN: 03875911
• NDL BIB ID: 030248320
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I030248320
• Web Site: https://www.jstage.jst.go.jp/article/kansenshogakuzasshi/94/1/94_102/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2020196834
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed