Peptide-assisted intracellular delivery of biomacromolecules

• Futaki, Shiroh

  Institute for Chemical Research, Kyoto University

• Arafiles, Jan Vincent V.

  Institute for Chemical Research, Kyoto University

• Hirose, Hisaaki

Abstract

Intracellular delivery of biomacromolecules offers opportunities for molecular and materials design, based on an understanding of their chemical properties and their modes of cellular responses. Peptides are advantageous as a delivery tool because of their ease in functional design and synthesis. This review highlights our approaches for the intracellular delivery of biomacromolecules using peptides with distinct modes of action.

Journal

• Chemistry Letters

  Chemistry Letters 49 (9), 1088-1094, 2020-09-15

  Chemical Society of Japan

Keywords

• Arginine-rich cell-penetrating peptide (CPP)
• Attenuated cationic membrane-lytic peptide
• Macropinocytosis-inducing peptide

Details

• CRID: 1050005667225847680
• NII Article ID: 130007897056
• ISSN: 03667022
• ISSN: 13480715
• DOI: 10.1246/cl.200392
• HANDLE: 2433/261238
• Web Site: http://www.journal.csj.jp/doi/pdf/10.1246/cl.200392
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN