Genome-wide changes in histone modification by repeated administration of chemicals

• ONO Ryuichi

  National Institute of Health Sciences (NIHS)

• AISAKI Ken-ichi

  National Institute of Health Sciences (NIHS)

• KITAJIMA Satoshi

  National Institute of Health Sciences (NIHS)

• KANNO Jun

  National Institute of Health Sciences (NIHS)

Bibliographic Information

Other Title

• 化学物質の反復投与によるゲノムワイドなヒストン修飾の変化

Abstract

Comprehensive bisulfite DNA methylation analyses and comprehensive histone modification analyses of the liver of male mice repeatedly orally exposed to carbon tetrachloride, valproic acid and clofibrate showed no major changes in DNA methylation status but showed genome-wide histone modification changes. We report the details of these histone modification changes.

Journal

• Annual Meeting of the Japanese Society of Toxicology

  Annual Meeting of the Japanese Society of Toxicology 47.1 (0), S21-5-, 2020

  The Japanese Society of Toxicology

Details

• CRID: 1390285697591719296
• NII Article ID: 130007898456
• DOI: 10.14869/toxpt.47.1.0_s21-5
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed