Effect of two doses of botulinum toxin type A on maximum plantar contact area in hemiplegic stroke patients with pes equinovarus

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  • Wada Yoshitaka
    Department of Anatomy, School of Medicine, Showa University Department of Rehabilitation Medicine, School of Medicine, Showa University Showa University Fujigaoka Rehabilitation Hospital
  • Otsuka Naruhito
    Department of Anatomy, School of Medicine, Showa University
  • Kawate Nobuyuki
    Department of Rehabilitation Medicine, School of Medicine, Showa University Showa University Fujigaoka Rehabilitation Hospital
  • Moriyama Hiroshi
    Department of Anatomy, School of Medicine, Showa University
  • Ezure Hiromitsu
    Department of Anatomy, School of Medicine, Showa University
  • Inoue Yuriko
    Department of Anatomy, School of Medicine, Showa University

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<p>Wada Y, Otsuka N, Kawate N, Moriyama H, Ezure H, Inoue Y. Effect of two doses of botulinum toxin type A on maximum plantar contact area in hemiplegic stroke patients with pes equinovarus. Jpn J Compr Rehabil Sci 2020; 11: 85-90.</p><p>Objectives: To quantitatively demonstrate the therapeutic effects of two doses of botulinum toxin type A (BoNT-A) on pes equinovarus in hemiplegic stroke patients.</p><p>Methods: The subjects of this study included eight chronic stroke patients who received two BoNT-A doses (mean dose interval: 136.0 (10.5) days) from April 2011 to March 2013 and underwent a sheet-type weight-bearing lower limb test. The maximum plantar contact area on the paralyzed side, ratio of maximum plantar contact areas on the paralyzed and non-paralyzed sides, and Modified Ashworth Scale (MAS) were measured before BoNT-A administration and 4 weeks after both the first and second doses.</p><p>Results: A significant increase in the maximum plantar contact area was observed after administration of the second dose compared to that of the first dose on the paralyzed side. Additionally, a significant increase was observed in the ratio of paralyzed/non-paralyzed maximum plantar contact areas after the administration of both the first and second doses compared to that before BoNT-A administration. MAS was observed to decline significantly after the administration of both the first and second doses compared to that prior to BoNT-A administration.</p><p>Conclusions: We suggest that comparison of the plantar contact area is useful for assessing the therapeutic effects of BoNT-A doses on pes equinovarus in hemiplegic stroke patients.</p>

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