Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion

  • Kusaba Yusaku
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Izumi Shinyu
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Takasaki Jin
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Suzuki Manabu
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Katagiri Daisuke
    Department of Nephrology, National Center for Global Health and Medicine, Japan
  • Katsuno Takashi
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Matsumoto Shuichiro
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Sakamoto Keita
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Hashimoto Masao
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Ohmagari Norio
    Diseases Control and Prevention Center, National Center for Global Health and Medicine, Japan
  • Katano Harutaka
    Department of Pathology, National Institute of Infectious Diseases, Japan
  • Suzuki Tadaki
    Department of Pathology, National Institute of Infectious Diseases, Japan
  • Hojo Masayuki
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
  • Sugiyama Haruhito
    Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan

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抄録

<p>An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 59 (19), 2405-2408, 2020-10-01

    一般社団法人 日本内科学会

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