Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion
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- Kusaba Yusaku
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Izumi Shinyu
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Takasaki Jin
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Suzuki Manabu
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Katagiri Daisuke
- Department of Nephrology, National Center for Global Health and Medicine, Japan
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- Katsuno Takashi
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Matsumoto Shuichiro
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Sakamoto Keita
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Hashimoto Masao
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Ohmagari Norio
- Diseases Control and Prevention Center, National Center for Global Health and Medicine, Japan
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- Katano Harutaka
- Department of Pathology, National Institute of Infectious Diseases, Japan
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- Suzuki Tadaki
- Department of Pathology, National Institute of Infectious Diseases, Japan
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- Hojo Masayuki
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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- Sugiyama Haruhito
- Department of Respiratory Medicine, National Center for Global Health and Medicine, Japan
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抄録
<p>An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 59 (19), 2405-2408, 2020-10-01
一般社団法人 日本内科学会