2－ヒドロキシプロピルメタクリルアミド系共重合体の合成と溶液物性

• 土居 聖将

  北九州市立大学大学院国際環境工学研究科

• 高橋 倫太郎

  北九州市立大学環境技術研究所

• 藤井 翔太

  北九州市立大学環境技術研究所

• 櫻井 和朗

  北九州市立大学環境技術研究所

書誌事項

タイトル別名

• Synthesis and Dilute Solution Properties of <i>N</i>-(2-Hydroxypropyl) methacrylamide-Based Copolymers

抄録

Poly[N-(2-Hydroxypropyl)methacrylamide] (PHPMA) shows excellent biocompatibility and thus is expected to be used as a carrier in a drug delivery system. In this study, we investigated how the difference in the monomer structure influences the sequence in copolymers composed of HPMA and monomers (MA-ahNHNH-Boc and MA-NHNH-Boc); the size of MA-ah-NHNH-Boc is larger than that of MA-NHNH-Boc by the alkyl chain (CH₂)₅ spacer. Because the obtained copolymers showed a phase separation behavior upon heating,we also investigated this phase separation behavior by turbidimetry and the molecular dimension in dilute aqueous solution by small-angle X-ray scattering (SAXS). Consequently, we found that the difference between the monomers (MA-ah-NHNH-Boc or MA-NHNH-Boc) significantly influences the monomer sequence in copolymer chains, the cloud point temperature, and the chain dimension in aqueous solution.

収録刊行物

• Journal of Fiber Science and Technology

  Journal of Fiber Science and Technology 76 (9), 305-309, 2020-09-15

  一般社団法人 繊維学会

キーワード

• Industrial and Manufacturing Engineering
• Polymers and Plastics
• Materials Science (miscellaneous)
• Chemical Engineering (miscellaneous)

詳細情報

• CRID: 1390848647561516288
• NII論文ID: 130007922388
• DOI: 10.2115/fiberst.2020-0033
• ISSN: 21897654
• Web Site: https://www.jstage.jst.go.jp/article/fiberst/76/9/76_2020-0033/_pdf
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可