Stimuli induced Structural Control of Sequential Alternating Amphiphilic Peptide coated Gold Nanoparticle Assemblies

• Ushiba Kae

• Higuchi Masahiro

• Kawaguchi Masami

Abstract

Gold nanoparticles having sequential alternating amphiphilic peptide chains, Phe-(Leu-Glu)8, on the surface have been prepared. We described structural control of the amphiphilic peptide coated gold nanoparticle assembly by a conformational transition of the surface peptides. Under the acidic condition, the conformation of the surface amphiphilic peptide was converted to a beta-sheet structure from an aggregated a-helix by incubation. The plasmon absorption maximum of the gold nanoparticles shifted to a shorter wavelength with the formation of the beta-sheet assembly of the surface peptide. This suggests that the structure of the peptide coated gold nanoparticle assembly could be controlled by the conformational transition of the surface peptide. Furthermore, the core gold nanoparticle could be fixed in the beta-sheet assembly in the state that stood alone. This system may be useful for novel molecular devices that exhibit quantized properties.

Journal

• Transactions of the Materials Research Society of Japan

  Transactions of the Materials Research Society of Japan 32 (2), 379-382, 2007

  The Materials Research Society of Japan

Keywords

• Sequential Alternating Amphiphilic Peptide
• Peptide Coated Gold Nanoparticle Assembly
• Conformational Transition
• Structural Control
• Plasmon Shift

Details

• CRID: 1390567172585065856
• NII Article ID: 130007922812
• DOI: 10.14723/tmrsj.32.379
• ISSN: 21881650
• ISSN: 13823469
• Web Site: https://www.jstage.jst.go.jp/article/tmrsj/32/2/32_379/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed