Utility of Kyoto Classification of Gastritis in subjects with a high-negative titer of anti-Helicobacter pylori antibody during a medical check-up
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- Otani Koji
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Watanabe Toshio
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Kosaka Satoshi
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Matsumoto Yuji
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Nakata Akinobu
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Nadatani Yuji
- Premier Preventive Medicine, Osaka City University Graduate School of Medicine
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- Fukunaga Shusei
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Hosomi Shuhei
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Tanaka Fumio
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Kamata Noriko
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Taira Koichi
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Nagami Yasuaki
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Tanigawa Tetsuya
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
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- Kimura Tatsuo
- Premier Preventive Medicine, Osaka City University Graduate School of Medicine
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- Fukumoto Shinya
- Premier Preventive Medicine, Osaka City University Graduate School of Medicine
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- Kawada Norifumi
- Premier Preventive Medicine, Osaka City University Graduate School of Medicine
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- Fujiwara Yasuhiro
- Departments of Gastroenterology, Osaka City University Graduate School of Medicine
書誌事項
- タイトル別名
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- Utility of Kyoto Classification of Gastritis in subjects with a high-negative titer of anti-<i>Helicobacter pylori</i> antibody during a medical check-up
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<p>Subjects with a high-negative titer (3–9.9 U/ml) of serum anti-Helicobacter pylori (H. pylori) antibody represent a heterogeneous group of currently H. pylori-infected, H. pylori-uninfected, and previously H. pylori-infected cases. We investigated the characteristics of subjects with a high-negative titer during a medical check-up and the utility of H. pylori infection score, the sum of scores of endoscopic findings based on the Kyoto Classification of Gastritis, for diagnosing H. pylori infection. Subjects with 13C-urea breath test-positive or H. pylori stool antigen test-positive were diagnosed as currently H. pylori-infected. Although around half of subjects with a high-negative titer were after eradication therapy (48.6%), currently H. pylori-infected were considerably confirmed (11.7%). H. pylori infection score showed a high value of area under the receiver operating characteristic curve [0.92; 95% confidence interval (CI), 0.84–1.00] with the most suitable cut-off value of 1.0 (sensitivity: 0.92; specificity: 0.90). Multivariate logistic regression analysis revealed that H. pylori infection score was an independent factor associated with increased prevalence of H. pylori infection (odds ratio, 9.53; 95% CI, 2.64–34.40; p<0.001). Currently H. pylori-infected subjects were considerably included among the subjects with a high-negative titer, and the Kyoto Classification of Gastritis was useful to predict current H. pylori infection.</p>
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｂｉｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｎｕｔｒｉｔｉｏｎ
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Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｂｉｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｎｕｔｒｉｔｉｏｎ 67 (3), 317-322, 2020
一般社団法人 日本酸化ストレス学会
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詳細情報 詳細情報について
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- CRID
- 1390849376468407424
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- NII論文ID
- 130007934157
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- ISSN
- 18805086
- 09120009
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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