Two Cases of Severe COVID-19 Pneumonia Effectively Treated with Extracorporeal Membrane Oxygenation in Addition to Favipiravir and Corticosteroid

  • Shinoda Masahiro
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Kamachi Kenichi
    Department of Surgery, Tokyo Shinagawa Hospital, Japan
  • Ota Shinichiro
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Yoshimatsu Lynn
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Boku Ryuichi
    Department of Emergency Medicine, Tokyo Shinagawa Hospital, Japan
  • Yoshida Yuto
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Hirouchi Takatomo
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Shinada Kanako
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Sato Takashi
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Morikawa Miwa
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan
  • Iwata Koki
    Department of Emergency Medicine, Tokyo Shinagawa Hospital, Japan
  • Matsumoto Takashi
    Department of Cardiology, Tokyo Shinagawa Hospital, Japan
  • Shinkai Masaharu
    Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Japan

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Abstract

<p>Case 1: A 65-year-old man with novel coronavirus infection (COVID-19) complicated with acute respiratory failure. On admission, the patient was started on favipiravir and corticosteroid. However, due to a lack of significant improvement, he was introduced to mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Although iliopsoas hematoma occurred as a complication, the patient recovered. Case 2: A 49-year-old man with COVID-19 had been started on favipiravir and corticosteroid. Due to progressive respiratory failure, the patient underwent mechanical ventilation and ECMO. The patient recovered without complications. We successfully treated these severe cases with a multimodal combination of pharmacological and non-pharmacological supportive therapy. </p>

Journal

  • Internal Medicine

    Internal Medicine 60 (1), 123-130, 2021-01-01

    The Japanese Society of Internal Medicine

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