Impact of Aperture Shape Controller on Knowledge-based VMAT Planning of Prostate Cancer

DOI Web Site Web Site PubMed 31 References
  • Ito Takaaki
    Department of Radiological Technology, Kobe City Nishi-Kobe Medical Center
  • Tamura Mikoto
    Department of Medical Physics, Graduate School of Medical Sciences, Kindai University
  • Monzen Hajime
    Department of Medical Physics, Graduate School of Medical Sciences, Kindai University
  • Matsumoto Kenji
    Department of Medical Physics, Graduate School of Medical Sciences, Kindai University Department of Radiology, Kindai University Hospital
  • Nakamatsu Kiyoshi
    Department of Radiation Oncology, Faculty of Medicine, Kindai University
  • Harada Tomoko
    Department of Radiological Technology, Kobe City Nishi-Kobe Medical Center
  • Fukui Tatsuya
    Department of Radiological Technology, Kobe City Nishi-Kobe Medical Center

Bibliographic Information

Other Title
  • 前立腺がんにおける知識ベース強度変調回転放射線治療計画へのaperture shape control 機能の影響
  • ゼンリツセン ガン ニ オケル チシキ ベース キョウド ヘンチョウ カイテン ホウシャセン チリョウ ケイカク エ ノ aperture shape control キノウ ノ エイキョウ

Search this article

Abstract

<p>Purpose: Knowledge-based planning (KBP) has disadvantages of high monitor unit (MU) and complex multi-leaf collimator (MLC) motion. We investigated the optimal aperture shape controller (ASC) level for the KBP to reduce these factors in volumetric modulated arc therapy (VMAT) for prostate cancer. Methods: The KBP model was created based on 51 clinical plans (CPs) of patients who underwent the VMAT for prostate cancer. Another 10 CPs were selected randomly, and the KBPs with/without ASC, changed stepwise from very low (KBP-VL) to very high (KBP-VH), were performed with a single auto-optimization. The parameters of dose-volume histograms (DVHs) and MLC performance metrics were evaluated. We obtained the modulation complexity score for VMAT (MCSv), closed leaf score (CLS), small aperture score (SAS), leaf travel (LT), and total MU. Results: The ASC did not affect the DVH parameters negatively. The following comparisons of MLC performance were obtained (KBP vs. KBP-VL vs. KBP-VH, respectively): 0.25 vs. 0.27 vs. 0.30 (MCSv), 0.19 vs. 0.18 vs. 0.16 (CLS), 0.50 vs. 0.45 vs. 0.40 (SAS10 mm), 0.73 vs. 0.68 vs. 0.63 (SAS20 mm), 768.35 mm vs. 671.50 mm vs. 551.32 mm (LT), and 672.87 vs. 642.36 vs. 607.59 (MU). There were significant differences between KBP and KBP-VH for MCSv and LT (p<0.05). Conclusions: The KBP using an ASC set to the very high level could reduce the complexity of MLC motion significantly more without deterioration of the DVH parameters compared with the KBP in VMAT for prostate cancer.</p>

Journal

References(31)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top