Effect of Vitamin E Supplementation on Deposition and Gene Expression Profiling of Abdominal Fat in Broiler Chickens

• Zhang Min

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Li Jianlei

  College of Life Science, Longyan University

• Zhu Yuting

  College of Life Science, Longyan University

• Wu Qiong

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Li Yan

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Huang Dingrui

  College of Life Science, Longyan University

• Gan Zhending

  College of Life Science, Longyan University

• Zhong Lipeng

  College of Life Science, Longyan University

• Huang Jingyu

  College of Life Science, Longyan University

• Li Hongyi

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Xu Weihua

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Zhang Mao

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Hung Qichun

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

• Sun Yanfa

  College of Life Science, Longyan University Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology Key Laboratory of Preventive Veterinary Medicine and Biotechnology (Longyan University)

抄録

The aim of this study was to study the regulation of abdominal fat deposition by DL-α-tocopherol acetate (vitamin E) in broilers. Diets supplemented with 50 IU vitamin E significantly diminished abdominal fat deposition in broilers at day 35. Transcriptome sequencing results for abdominal fat tissues of the control (FC) and 50 IU vitamin E-supplemented (FT) groups identified 602 differentially expressed genes (DEGs), which were enriched in cellular process, cell and cell part, and binding Gene Ontology terms. Pathway functional analysis revealed that the DEGs were enriched in 42 metabolic pathways. Notably, the most enriched pathway, fatty acid biosynthesis, was found to play a key role in lipid metabolism. Further, the key regulators of lipid metabolism, including fatty acid synthase, acetyl-CoA carboxylase alpha, and acyl-CoA synthetase long-chain family member 1, demonstrated decreased expression following vitamin E supplementation. Herein, we have identified pathways and genes regulated by vitamin E, thereby providing novel insights into the nutrients regulating abdominal fat deposition in broilers.

収録刊行物

• The Journal of Poultry Science

  The Journal of Poultry Science 58 (1), 40-50, 2021

  日本家禽学会

キーワード

• abdominal fat deposition
• broiler
• gene expression
• RNA-seq
• vitamin E

詳細情報

• CRID: 1391975831238965376
• NII論文ID: 130007975348
• NII書誌ID: AA11564513
• DOI: 10.2141/jpsa.0200011
• ISSN: 13490486
• ISSN: 13467395
• NDL書誌ID: 031226114
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I031226114
• Web Site: https://www.jstage.jst.go.jp/article/jpsa/58/1/58_0200011/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可