Risk of Herpes Zoster in Relation to Body Mass Index Among Residents Aged ≥50 Years: The Shozu Herpes Zoster Study
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- Kawahira Kazuhiro
- Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine Cosmo Medical Clinic
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- Imano Hironori
- Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine
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- Yamada Keiko
- Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine Department of Psychology, McGill University Department of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine
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- Takao Yukiko
- Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine
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- Mori Yasuko
- Graduate School of Medicine, Center for Infectious Diseases, Kobe University
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- Asada Hideo
- Department of Dermatology, Nara Medical University School of Medicine
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- Okuno Yoshinobu
- Osaka Institute of Public Health
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- Yamanishi Koichi
- The Research Foundation for Microbial Diseases of Osaka University
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- Iso Hiroyasu
- Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine Department of Public Health Medicine, Faculty of Medicine, University of Tsukuba
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<p>Background: The impact of body mass index on incidence of herpes zoster is unclear. This study investigated whether body mass index was associated with a history of herpes zoster and incidence during a 3-year follow-up, using data from a prospective cohort study in Japan.</p><p>Methods: In total, 12,311 individuals were included in the cross-sectional analysis at baseline, of whom 1,818 with a history of herpes zoster were excluded from the incidence analysis, leaving 10,493 individuals. Body mass index (kg/m2) was classified into three categories (underweight: <18.5; normal: 18.5 to <25; and overweight: ≥25). To evaluate the risk of herpes zoster, we used a logistic regression model for prevalence and a Cox proportional hazard regression model for incidence.</p><p>Results: Being overweight or underweight was not associated with herpes zoster prevalence at baseline. The multivariate hazard ratios of herpes zoster incidence for overweight versus normal-weight groups were 0.67 (95% confidence interval, 0.51–0.90) in all participants, and 0.57 (95% confidence interval, 0.39–0.83) in women, with no significant difference for men.</p><p>Conclusion: Being overweight was associated with a lower incidence of herpes zoster than being normal weight in older Japanese women.</p>
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｅｐｉｄｅｍｉｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｅｐｉｄｅｍｉｏｌｏｇｙ 32 (8), 370-375, 2022-08-05
日本疫学会
