Integration of Neuro-regenerative Medicine and Robot Rehabilitation

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  • Yuge Louis
    Division of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Mitsuhara Takafumi
    Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Kurisu Kaoru
    Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University Chugoku Rosai Hospital

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  • 神経再生医療とロボットリハビリテーションの統合

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Abstract

<p>  Regenerative medicine studies using mesenchymal stem cells, which are somatic stem cells, have already been conducted as clinical studies and clinical trials in Japan and overseas, mainly for cerebral infarction and spinal cord injury. Our work has focused on neural crest-derived mesenchymal stem cells that have the same origin as the nervous system, and recently established mesenchymal stem cells from the skull. Skull-derived mesenchymal stem cells have superior properties in neuroregeneration therapy and in terms of safety and efficacy for cell therapy compared with commonly used mesenchymal stem cells derived from the mesoderm, such as the bone marrow. We are currently conducting clinical research to confirm these results.</p><p>  On the other hand, regenerative medicine is considered to be a new treatment modality as a radical treatment procedure or strategy that does not leave sequelae or disorders . However, as clinical trials progress, the importance of rehabilitation after stem cell transplantation is being understood. We are also studying and developing walking support robots for regenerative medicine, and are proceeding with the integration of cell therapy and robot rehabilitation using in-house data.</p>

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