Prevalence of Barrett's Epithelium Shown by Endoscopic Observations with Linked Color Imaging in Subjects with Different <i>H. pylori</i> Infection Statuses
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- Adachi Kyoichi
- Health Center, Shimane Environment and Health Public Corporation, Japan
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- Ishimura Norihisa
- Second Department of Internal Medicine, Shimane University Faculty of Medicine, Japan
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- Kishi Kanako
- Health Center, Shimane Environment and Health Public Corporation, Japan
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- Notsu Takumi
- Health Center, Shimane Environment and Health Public Corporation, Japan
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- Mishiro Tomoko
- Health Center, Shimane Environment and Health Public Corporation, Japan
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- Sota Kazunari
- Health Center, Shimane Environment and Health Public Corporation, Japan
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- Ishihara Shunji
- Second Department of Internal Medicine, Shimane University Faculty of Medicine, Japan
Bibliographic Information
- Other Title
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- Prevalence of Barrett’s Epithelium Shown by Endoscopic Observations with Linked Color Imaging in Subjects with Different H. pylori Infection Statuses
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Abstract
<p>Objective This study was conducted to clarify the prevalence of short segment Barrett's esophagus (SSBE) using endoscopic observations with linked color imaging (LCI). In addition, the relationship between the presence of Barrett's epithelium (BE) and the status of H. pylori infection was investigated. </p><p>Methods The study subjects were 3,353 individuals (2,186 men, 1,167 women; mean age 55.2±9.4 years old) whose status of H. pylori infection had been determined. An endoscopic observation using LCI was performed to examine the distal margin of palisade vessels and confirm the area of BE. The prevalence of BE ≥5 mm in length was investigated. </p><p>Results BE was diagnosed in 1,884 (56.2%) subjects, with lengths of <10, 10-19, 20-29, and ≥30 mm found in 1,005, 851, 27, and 1, respectively. Its prevalence in H. pylori-negative, H. pylori-positive, and post-eradicated subjects was 41.7%, 64.4%, and 69.9%, respectively (p<0.001). The duration since successful eradication of H. pylori did not affect the prevalence of BE. The degree of gastric mucosal atrophy was higher in cases with BE (p<0.001), although negativity for H. pylori infection and mild gastric mucosal atrophy were significant factors for the development of longer BE. </p><p>Conclusion A high prevalence of SSBE was noted when LCI was used to determine the area of BE, as the distal end of the palisade vessels was easily visualized. Negativity for H. pylori infection and mild gastric mucosal atrophy were not correlated with SSBE prevalence. </p>
Journal
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- Internal Medicine
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Internal Medicine 60 (5), 667-674, 2021-03-01
The Japanese Society of Internal Medicine
