Improvement of Skeletal Muscle Mass after Ledipasvir and Sofosbuvir Treatment for Hepatitis C Virus in Decompensated Liver Cirrhosis
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- Sakamori Ryotaro
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Yamada Ryoko
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Shinkai Kazuma
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Doi Akira
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Tahata Yuki
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Shigekawa Minoru
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Kodama Takahiro
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Hikita Hayato
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Yamada Tomomi
- Department of Medical Innovation, Osaka University Hospital, Japan
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- Tatsumi Tomohide
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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- Takehara Tetsuo
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan
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抄録
<p>Hepatitis C virus (HCV) can be eliminated by direct-acting antivirals in patients with decompensated liver cirrhosis. Although viral clearance in decompensated liver cirrhosis leads to improvement of the liver function and quality of life, changes in the skeletal muscle mass after sustained virologic response (SVR) in patients with decompensated liver cirrhosis have not been reported. We present the first report of skeletal muscle mass improvement with the achievement of SVR for HCV in a 76-year-old woman with decompensated liver cirrhosis. After achieving SVR through ledipasvir/sofosbuvir treatment, the patient showed an improvement in her liver function and an increase in her skeletal muscle mass. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 60 (5), 745-750, 2021-03-01
一般社団法人 日本内科学会