Bio-inert Properties of TEG Modified Dendrimer Interface

• MIURA Yoshiko

  Department of Chemical Engineering, Kyushu University

• KOJIMA Yuki

  Department of Chemical Engineering, Kyushu University

• SETO Hirokazu

  Department of Chemical Engineering, Kyushu University

• HOSHINO Yu

  Department of Chemical Engineering, Kyushu University

抄録

The bioinert interfaces that prevent adhesion of proteins and cells are important for biomaterial applications. In order to design a bioinert interface, the immobilization of an appropriate functional group and the control of molecular density is required. Dendrimer was modified with triethylene glycol (TEG) to display a dense brush structure. TEG with different density and terminal groups were immobilized with a dendrimer template and thiol terminated molecules. The inhibitory effect on protein and bacteria binding was investigated. The physical property of the interface was measured by QCM-admittance to clarify the factor of the bioinert property.

収録刊行物

• Analytical Sciences

  Analytical Sciences 37 (3), 519-523, 2021-03-10

  社団法人 日本分析化学会

キーワード

• Bioinert interface
• dendrimer
• triethylene glycol
• QCM-A

詳細情報

• CRID: 1390287297545590400
• NII論文ID: 130007996266
• NII書誌ID: AA12022210
• DOI: 10.2116/analsci.20p388
• ISSN: 13482246
• ISSN: 09106340
• HANDLE: 2324/4479684
• NDL書誌ID: 031326400
• PubMed: 33310990
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I031326400
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.20P388.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.20P388/fulltext.html
• Web Site: https://www.jstage.jst.go.jp/article/analsci/37/3/37_20P388/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2022057691
• 本文言語コード: en
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