Anti-aging Medical Check-up and Evidence of Its Benefits

DOI
  • Yonei Yoshikazu
    Anti-Aging Medical Research Center/Glycative Stress Research Center, Graduate School of Life and Medical Sciences, Doshisha University
  • Yagi Masayuki
    Anti-Aging Medical Research Center/Glycative Stress Research Center, Graduate School of Life and Medical Sciences, Doshisha University
  • Meno Manami
    Anti-Aging Medical Research Center/Glycative Stress Research Center, Graduate School of Life and Medical Sciences, Doshisha University

Search this article

Abstract

<p>  The Yurin Study has been conducted since 2008 to promote health-related training to about 40 independent older adults, mainly through walking and conducting annual anti-aging medical check-up (AAMC). The aim was to prevent aging and rejuvenate the body by evaluating its functional age and identifying the parts that have aged the most.</p><p>  Muscle age, vascular age, neural age, hormonal age, and bone age were evaluated as the functional age in AAMC. Immune stress, oxidative stress, physical and mental stress, glycative stress, and lifestyle were assessed as risk factors of aging using scores. The analysis outcomes from various perspectives are presented in this paper.</p><p>  The participants (20) of AAMC—conducted three times between 2012–2014—showed a decrease in HbA1c and skin AGE fluorescence, which are glycative stress indicators. The results of a medication compliance survey (39 participants) conducted in 2016 showed the use of medication for high blood pressure in 21 participants; dyslipidemia in 11; osteoporosis in 10; gastric acid secretion inhibitors in 9; and non-steroidal anti-inflammatory agents, antidiabetic drugs, and sleep-inducing medication in 5 each. Many of those who were on medication had a younger functional age than their actual age. When the results of the 2015 analysis, wherein participants of the Yurin Study who led independent daily lives (43 participants) were compared with those requiring support and visiting a daycare facility (31 participants) and those requiring nursing care and residing in a health care facility for the elderly (19 participants), it was found that the participants of the Yurin Study maintained a younger neural age. An analysis of age-related transitions in plasma amyloid beta (Aβ) 40/42 ratio in 2019 revealed that the elevation in the ratio tended to be higher in the elderly than in the young, middle-aged, and older people.</p><p>  We expect that the data collected from the AAMC will provide useful information for the promotion of public health.</p>

Journal

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top