Factors Associated with Self-reported Medication Adherence in Japanese Community-dwelling Elderly Individuals: The Nakajima Study

  • Ishida Natsuko
    Clinical Pharmacy and Healthcare Sciences, Faculty of Pharmacy, Institute of Medical, Pharmaceutical & Health Science, Kanazawa University
  • Tokumoto Yurina
    Clinical Pharmacy and Healthcare Sciences, Faculty of Pharmacy, Institute of Medical, Pharmaceutical & Health Science, Kanazawa University
  • Suga Yukio
    Clinical Pharmacy and Healthcare Sciences, Faculty of Pharmacy, Institute of Medical, Pharmaceutical & Health Science, Kanazawa University
  • Noguchi-Shinohara Moeko
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Abe Chiemi
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Yuki-Nozaki Sohshi
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Mori Ayaka
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Horimoto Mai
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Hayashi Koji
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Iwasa Kazuo
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences
  • Yokogawa Masami
    Department of Physical Therapy, Division of Health Sciences, Kanazawa University Graduate School of Medical Sciences
  • Ishimiya Mai
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Sciences
  • Nakamura Hiroyuki
    Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Sciences
  • Komai Kiyonobu
    Department of Neurology, Hokuriku Brain and Neuromuscular Disease Center, Iou Hospital, National Hospital Organization
  • Matsushita Ryo
    Clinical Pharmacy and Healthcare Sciences, Faculty of Pharmacy, Institute of Medical, Pharmaceutical & Health Science, Kanazawa University
  • Ishizaki Junko
    Clinical Pharmacy and Healthcare Sciences, Faculty of Pharmacy, Institute of Medical, Pharmaceutical & Health Science, Kanazawa University
  • Yamada Masahito
    Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences

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Abstract

<p>Medication non-adherence in the elderly population is a major problem, preventing them from obtaining optimal therapeutic effects. Identifying the factors affecting medication adherence is crucial for improving and maintaining health among the elderly population and enhance healthcare economy. The purpose of this study was to examine the prevalence of self-reported medication adherence, and identify the associated factors and the influence of health-related quality of life (HRQOL) in the Japanese community-dwelling elderly population. This cross-sectional study was part of the Nakajima study and targeted inhabitants aged ≥60 years who underwent health examinations in 2017. Data regarding medication adherence were acquired through interviews and self-administered questionnaires. Medication adherence were assessed using a visual analog scale, and HRQOL was assessed by EuroQol five-dimensional questionnaire with 3 levels. Among the 455 participants, low and high medication adherence were seen in 9.7% and 66.2% of the participants, respectively (visual analog scores <80% and ≥95%, respectively). Medication adherence was significantly lower in participants taking medications ≥3 times daily than in those taking medications once or twice daily; a regimen involving drug administration ≥3 times daily had significantly lower odds of medication adherence. The use of a drug profile book and HRQOL had significant positive association with medication adherence. Our results suggest that low dosing frequency and using a drug profile book was positively associated with medication adherence among elderly persons, which in turn could enhance their QOL.</p>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 141 (5), 751-759, 2021-05-01

    The Pharmaceutical Society of Japan

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