Evaluation of the mechanical properties and biocompatibility of gypsum-containing calcium silicate cements
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- HAYASHI Yumiyo
- Department of Endodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- KAWAKI Harumi
- Department of Oral Biochemistry, Division of Oral Structure, Function, and Development, Asahi University School of Dentistry
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- HORI Masaharu
- Department of Endodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- SHINTANI Kohei
- Department of Dental Materials Science, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- HASEGAWA Tomoya
- Department of Endodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- TANAKA Masashi
- Department of Endodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- KONDOH Nobuo
- Department of Oral Biochemistry, Division of Oral Structure, Function, and Development, Asahi University School of Dentistry
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- YOSHIDA Takakazu
- Department of Endodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- KAWANO Satoshi
- Department of Endodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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- TAMAKI Yukimichi
- Department of Dental Materials Science, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry
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Abstract
<p>Mineral trioxide aggregate (MTA) cement is widely used in the field of endodontic treatment. We herein synthesized calcium silicates from calcium carbonate and silicon dioxide, with the aim of reducing the cost associated with the MTA. Additionally, we prepared gypsum-containing calcium silicate cement to reduce the setting time while enhancing the mechanical strength. We evaluated the physical properties of this cement and investigated the response of human dental pulp stem cells (hDPSCs) grown in culture media containing cement eluate. Our results revealed that calcium silicates could be easily synthesized in lab-scale. Furthermore, we demonstrate that gypsum addition helps shorten the setting time while increasing the compressive strength of dental cements. The synthesized gypsum-containing calcium silicate cement showed minimal cytotoxicity and did not inhibit the proliferation of hDPSCs. These results suggested that the newly developed calcium silicate material could be a promising pulp capping material.</p>
Journal
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- Dental Materials Journal
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Dental Materials Journal 40 (4), 863-869, 2021-07-25
The Japanese Society for Dental Materials and Devices