Impact of Valve Plane Alignment on the Repeatability of Left Ventricular Ejection Fraction in ECG-gated Myocardial SPECT Using Corridor 4DM

• Rambow Franziska

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Gersdorf Denis

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Jacobi Janin

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Mathies Franziska

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Klene Christiane

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Zsebe Zsofia

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Klutmann Susanne

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Apostolova Ivayla

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

• Nakajima Kenichi

  Department of Functional Imaging and Artificial Intelligence, Kanazawa University Graduate School of Medicine

• Mester Janos

  Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Centre Hamburg-Eppendorf

抄録

Background: In myocardial gated single-photon emission computed tomography (GSPECT), to differentiate true changes of left ventricular ejection fraction (LVEF) from inherent methodical variability is clinically relevant; however, data about repeatability of GSPECT LVEF in the same patients are rather inconsistent in literature. The aim of this study was therefore to determine repeatability coefficient (RC) of GSPECT LVEF at rest and to investigate the effect of the introduction of processing constraints in left ventricular edge detection.<br>Methods: Thirty-five patients referred for one-day myocardial GSPECT stress-rest scan were included. After the routine stress-rest study, patients were completely repositioned on the imaging table for a second rest acquisition using the same acquisition parameters. LVEF was computed using Corridor 4DM software without and with manual alignment of valve plane. Repeatability was assessed using the Bland-Altman method.<br>Results: RC of LVEF from unaligned datasets was 7.6% with upper and lower limits of agreement of 7.4% to -7.8%. After valve plane and ventricular long-axis length alignment, RC improved to 3.6% with upper and lower limits of agreement of 3.4% to -3.8%.<br>Conclusions: RC using unaligned determination of GSPECT LVEF was comparable to that from previous publications. However, RC using valve plane alignment could be improved to below 4% on 95% confidence level.

収録刊行物

• Annals of Nuclear Cardiology

  Annals of Nuclear Cardiology 7 (1), 27-32, 2021-08-31

  日本心臓核医学会

キーワード

• ^99mTc-Sestamibi
• Coefficient of repeatability
• Ejection fraction
• Gated-SPECT
• Left ventricular function

詳細情報

• CRID: 1390289225019655552
• NII論文ID: 130008081341
• DOI: 10.17996/anc.21-00138
• ISSN: 24241741
• ISSN: 21893926
• Web Site: https://www.jstage.jst.go.jp/article/anc/7/1/7_21-00138/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2022197601
• 本文言語コード: en
• データソース種別:
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