Myocardial T<sub>1</sub>-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
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- Koyanagawa Kazuhiro
- Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
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- Kobayashi Yuta
- Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
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- Aikawa Tadao
- Department of Radiology, Jichi Medical University Saitama Medical Center
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- Takeda Atsuhito
- Department of Pediatrics, Hokkaido University Hospital
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- Shiraishi Hideaki
- Department of Pediatrics, Hokkaido University Hospital
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- Tsuneta Satonori
- Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital
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- Oyama-Manabe Noriko
- Department of Radiology, Jichi Medical University Saitama Medical Center
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- Iwano Hiroyuki
- Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
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- Nagai Toshiyuki
- Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
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- Anzai Toshihisa
- Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
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抄録
<p>To assess myocardial fibrosis associated with muscular dystrophy, T1-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dystrophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.</p>
収録刊行物
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- Magnetic Resonance in Medical Sciences
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Magnetic Resonance in Medical Sciences 20 (3), 320-324, 2021
日本磁気共鳴医学会
