後天性von Willebrand症候群患者の抜歯経験

DOI Web Site Web Site 参考文献10件
  • 澤木 廉
    名古屋大学医学部附属病院歯科口腔外科 豊田厚生病院歯科口腔外科
  • 岡部 一登
    名古屋大学医学部附属病院歯科口腔外科
  • 坂口 晃平
    名古屋大学医学部附属病院歯科口腔外科
  • 坂倉 寛紀
    名古屋第二赤十字病院歯科口腔外科
  • 兼子 隆次
    豊田厚生病院歯科口腔外科
  • 日比 英晴
    名古屋大学医学部附属病院歯科口腔外科 名古屋大学大学院医学系研究科頭頸部感覚器外科学講座顎顔面外科学

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タイトル別名
  • A case involving tooth extraction in a patient with acquired von Willebrand syndrome
  • コウテンセイ von Willebrand ショウコウグン カンジャ ノ バッシ ケイケン

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<p>A 42-year-old woman diagnosed with acquired von Willebrand syndrome (AvWS) was referred to our department for pain in the left mandibular third molar. vWF-containing concentrates (Confact F®) were transfused before and after tooth extraction for hemostatic management. Although initial hemostasis was achieved, persistent postoperative bleeding was observed 3 days later. Therefore, additional hemostatic management using a mouth splint with gingival packing and increased transfusion of Confact F® was required. After this, no further bleeding was observed, and the administration of Confact F® was ceased 14 days post-operation. The stitches were removed 24 days post-operation. Two years and 11 months after the operation, the clinical course is good. The pathophysiology of AvWS has not been elucidated, and an effective treatment has not yet been established. Therefore, reliable hemostatic management in cooperation with hematology is necessary.</p>

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