District Differences in the Measured Values of Arterial Stiffness in Japan
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- Miyai Nobuyuki
- School of Health and Nursing Science, Wakayama Medical University
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- Uchiba Kiyoshi
- Ooka Clinic
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- Tomiyama Hirofumi
- Department of Cardiology, Tokyo Medical University
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- Matsumoto Chisa
- Department of Cardiology, Tokyo Medical University
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- Kinoshita Azuna
- School of Health and Nursing Science, Wakayama Medical University
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- Vlachoupolos Charalambos
- Hypertension and Cardiometabolic Unit, First Department of Cardiology, Hippokration Hospital, Medical School, National and Kapodistrian University of Athens
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- Nilsson Peter M.
- Department of Clinical Sciences, Lund University, Skane University Hospital
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- Arita Mikio
- Department of Cardiology, Sumiya Rehabilitation Hospital
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<p>Background:In Japan, district differences in the prevalence of cardiovascular disease (CVD) are well-known. This study examined district differences in Japan in measured values of arterial stiffness, an independent risk factor for CVD.</p><p>Methods and Results:Local residents participating in health checkups conducted in the Wakayama (n=461) and Nagano (n=186) prefectures in 2018 were recruited to the study. Brachial-ankle pulse wave velocity (baPWV) was evaluated as an index of arterial stiffness. After multivariate adjustment, baPWV was significantly higher in the Wakayama than Nagano district in subjects aged ≥70 years (mean [±SE] 1,912±25 vs. 1,763±30 cm/s; P<0.01), but not in subjects aged <70 years. Multivariate linear regression analysis demonstrated that the Wakayama/Nagano district difference was significantly (P<0.01) associated with baPWV.</p><p>Conclusions:District differences were observed in the measured values of arterial stiffness in Wakayama and Nagano. The Wakayama and Nagano prefectures are representative areas with a relatively high and relatively low prevalence of CVD, respectively, in Japan. Therefore, based on the results of the present study, we propose to conduct a study to examine whether district differences in arterial stiffness underlie district differences in the prevalence of CVD.</p>
収録刊行物
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- Circulation Reports
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Circulation Reports 3 (10), 620-624, 2021-10-08
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390852591667760000
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- NII論文ID
- 130008102379
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- ISSN
- 24340790
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
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- KAKEN
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